Chronic inhalation has also caused hemolytic anemia. It can also cause nausea, vomiting, abdominal pain, seizures and coma. Clinically, patients present with acute onset of dark brown urine, watery diarrhea, and non-bloody bilious vomiting 48-96 hours after exposure. If you or someone you know has been regularly inhaling moth balls or their fumes, take them to the doctor immediately. A 33-year-old Sri Lankan woman Naphthalene Toxicity: Methemoglobinemia and Acute Intravascular Hemolysis Abstract. Inhalation. This website provides easy access to all the pesticide-related information that is contained in various pesticide topical sites. the dosage, formulation, labelling, packaging and presentation of a substance: The presence of respiratory tract tumors in animals following naphthalene exposure by inhalation is sufficient to demonstrate carcinogenicity in these model systems, but the quantification of human cancer risk at low exposure levels based on these studies is a point of considerable debate. (1992). Can you sleep in a room with naphthalene balls/mothballs? For the highest residential exposure scenario to naphthalene acetates, estimated dermal and inhalation exposure are low and do not pose risks of concern. Acute Toxicity 3.3.1.1. Exposed to Naphthalene by Inhalation for Their Lifetime .. 7-15 Table 7-4. Humans, particularly children, have developed hemolytic anemia after ingesting mothballs or deodorant blocks containing naphthalene. 5.4). Alcohol used in cleaners are poisonous. This article is for information only. In the nose, naphthalene exposure was with associated an increage the in incidence and severity of chronic inflammation, metaplasia of the olfactory epithelium, and hyper- plasia of People are most likely to be exposed to Extended exposure to the vapors may result in cataract formation and liver damage.
This can cause organ damage. Naphthalene poisoning (or mothball poisoning) is a form of poisoning that occurs when naphthalene is ingested. the dosage, formulation, labelling, packaging and presentation of a substance: Reference values for naphthalene derived by the U.S. EPA and other national, state, and international agencies are depicted in Figure 1 (inhalation exposure) and Figure 2 (oral exposure). Naphthalene inhalation and ingestion can cause headaches, nausea, extensive sweating, and confusion. Short-term exposure guidelines: None developed.
It can affect how blood carries oxygen to the heart, brain, and other organs. Naphthalene. Naphthalene is a white solid substance with a strong smell.
Breathing in the fumes over a period of time can cause poisoning, too. It is well absorbed following oral, dermal and inhalation exposure. As discussed in Chapter 2 and Appendix A, several MRLs for naphthalene (chronic-duration inhalation, acute-duration oral, and intermediate-duration oral) and chronic-duration oral MRLs for 1-methylnaph-thalene and 2-methylnaphthalene have been derived. Accidental poisoning with naphthalene occurs much more commonly than is reported in biomedical literature .
OTHER ROUTES OF EXPOSURE 3.3.1. Over time, long-term exposure to naphthalene can lead to an anemia. Airport personnel are at risk of occupational exposure to jet engine emissions, which similarly to diesel exhaust emissions include volatile organic compounds and particulate matter consisting of an inorganic carbon core with associated polycyclic aromatic hydrocarbons, and metals. A. Terminal Body Weights in Controls and in Fischer 344 Rats Exposed to Naphthalene by Gavage for 13 Weeks.. 7-8 Table 7-2. Naphthalene Trace 91-20-3 Sulphur Trace 7704-34-9 2. Definition: Naphthalene is a white solid substance with a strong smell. This can cause organ damage. is the primary route of entry for hazardous chemicals in the work environment. Naphthalene Poisoning following Ingestion of Mothballs: A Case Report Abstract. Rare cases of mothball Also, 1,4-DCB is also known to cause effects similar to those of
The cancer potency of naphthalene was estimated from dose-response data for benign and malignant tumors among male rats exposed via inhalation to naphthalene by the National Toxicology Program (NTP, 2000). Naphthalene poisoning. (2010) Nasal Olfactory Epithelial Lesions in F344 and SD Rats Following 1- and 5-Day Inhalation Exposure to Naphthalene Vapor. Industrial naphthalene-fume poisoning, chiefly with skin manifestations (Touraine and Menetrel 1934, Fanburg 1940) and especially naphthalene cataract (Bouchard and Charrin 1886, Michail and Vancea 1927) have also been often reported and investigated. For certain uses, consider hydrogen peroxide. Mortality resulting from exposure to chlorinated naphthalene fumes has been reported.3 4 The most f Inhaling Naphthalene can irritate the nose and throat. Naphthalene and paradichlorobenzene are two ingredients used in People can experience anemia after several years of exposure to naphthalene. The most likely source of exposure to significant amounts of naphthalene is occupational inhalation of the vapour, since its principal use is in industry [1]. The LD 50 is 1.8 g/kg in adult rats. Naphthalene is readily absorbed through the skin and can cause skin irritation, corneal ulcerations, and cataracts (Refs. It also includes news and meeting information, an A-Z index, and more. This article is for information only. Exposure to Naphthalene in Media Other than Water .. 5-8 Table 7-1. Symptoms of severe poisoning are vomiting, then coma, and hematuria (Ref. As little as 250500 mg may produce hemolysis in a patient with G6PD deficiency. The nose is the most sensitive toxicity target in rats and mice following chronic inhalation exposure to naphthalene. Exposure to naphthalene commonly causes headache, nausea, vomiting, diarrhea, abdominal pain, fever, and altered mental status. B. Repeated exposure to naphthalene can cause clouding of the eyes lens and damage vision. You can be exposed to a pesticide if you breathe it in, get it on your skin, or if you accidentally eat or drink something containing a pesticide. There may be dysuria, haematuria and an acute haemolytic reaction. Symptoms include weakness, dizziness, fatigue and fainting. fNaphthalene may damage the liver and kidneys. Paradichlorobenzene acute ingestions are virtually always innocuous. The US EPA has classified naphthalene as a Group C, possible human carcinogen. Although naphthalene was widely used industrially, only nine cases of poisoning have been Rarely optic neuritis is encountered. Technical Report Series No. However, the general public may be exposed to naphthalene through inhalation of smoke from burning fossil fuels or wood, or from inhaling vehicle exhaust fumes. During inhalation, each alveoli receives air that contains various gases: nitrogen (almost 80%), oxygen (almost 20%) and other gases including 0.04% carbon dioxide. Naphthalene is also a possible carcinogen. As little as one mothball can result in toxicity in children. If there are no exceedances for both 2-methylnaphthalene and naphthalene for all contingency samples, then remediation is complete for 2-methylnaphthalene and naphthalene.
We found that the loss of hepatic naphthalene metabolism severely decreased naphthalene systemic clearance and caused naphthalene to accumulate in the liver and other tissues. Exposure to large amounts of naphthalene may cause confusion, nausea, vomiting, diarrhea, blood in the urine, and jaundice (yellow coloration of the skin due to dysfunction of the liver). presence of respiratory tract tumors in animals following naphthalene exposure by inhalation is sufficient to demonstrate carcinogenicity in these model systems, but the quantification of human cancer risk at low exposure levels based on these studies is a point of considerable debate. Naphthalene Methemoglobinemia Hemolytic anemia Metabolic acidosis Seizures 1. Safety Data Sheet Review The amount necessary to produce lethargy or seizures is not known but may be as little as 12 g. Several infants developed serious poisoning from clothes and bedding that had been stored in naphthalene mothballs. ( naf'th-ln ), A carcinogenic and toxic hydrocarbon obtained from coal tar; used for many syntheses in industry and in some moth repellents; naphthalene can cause an attack of hemolytic anemia in people with a deficiency of glucose-6-phosphate dehydrogenase. guidance. f Exposure to Naphthalene may cause a skin allergy. Acute lung toxicity and carcinogenesis are thought to be related because the target sites for both are similar. Naphthalene is a widely used industrial and household chemical in the form of mothballs. Inhalation REL (ug/m 3) Oral REL (ug/kg BW-day) Hazard Index Target Organs . Agitation, lethargy, and seizures may occur with naphthalene ingestion. Summary table of all OEHHA acute, 8-hr and chronic Reference Exposure Levels (chRELs) as of November 2019. This contrasts with the structure of benzene, in which all the CC bonds have a common length, 1.39 . Naphthalene is more reactive than benzene, both in substitution and addition reactions, and these reactions tend to proceed in a manner that maintains one intact benzene ring. NIH Publication No. These experts collectively have knowledge of naphthalene, 1-methylnaphthalene, and 2-methyl naphthalene's physical and chemical properties, toxicokinetics, key health end points, mechanisms of action, human and animal exposure, and quantification of Naphthalene poisoning is a rare form of toxicity that may occur after ingestion, inhalation, or dermal exposure to naphthalene-containing compounds such as mothballs. DO NOT use it to treat or manage an actual poison exposure. Lead acetate oral cancer and inhalation cancer updated. Prolonged exposure can lead to liver damage and cataract formation. Exposure to large amounts of naphthalene may damage or destroy red blood cells.
Definition: Naphthalene is a white solid substance with a strong smell. Ingestion, either accidental or by deliberate self-harm, can occur due to its abundance as well as its candy-resembling appearance. These odor thresholds for naphthalene are below the regulated level of 10 ppm for occupational exposure, so people can smell this chemical before conditions are hazardous. Naphthalene (mothball) is a commonly used deodorizer in the Indian subcontinent, including Sri Lanka. Human exposure to naphthalene is primarily through inhalation, although it can be ingested and absorbed through the skin. The chosen IDLH, therefore, has been estimated from the probable oral lethal dose of 5 to 15 grams for an adult [Gerarde 1960 cited by AIHA 1967]. Benzo[a]pyrene is a polycyclic aromatic hydrocarbon and the result of incomplete combustion of organic matter at temperatures between 300 C (572 F) and 600 C (1,112 F).The ubiquitous compound can be found in coal tar, tobacco smoke and many foods, especially grilled meats. Severe poisoning can result in haemolytic anaemia. concentration exceeds the inhalation exposure pathway residential direct contact criterion of 6 mg/kg. In the nose, naphthalene exposure was with associated an increage the in incidence and severity of chronic inflammation, metaplasia of the olfactory epithelium, and hyper- plasia of Ingestion in large amounts could lead to blindness and even death. Gene expression data in naive mice were consistent with the concept that female juvenile mice are more predisposed to DNA damage and lung tumors than the other groups. Diesel exhaust is classified as carcinogenic and the particulate fraction has in itself been Half of the mice were given the GSH depletor diethylmaleate (DEM) 1 hour before naphthalene exposure.
No exposure-related gross pathologic lesions were observed at necropsy. Inhalation: On inhalation naphthalene cases headache, confusion, excitement, nausea, vomiting and sweating. Long-term exposure may be related to sinus and throat cancers. Poisoning from naphthalene destroys or changes red blood cells so they cannot carry oxygen. Both chemicals are toxic and known to cause dizziness, headaches, and irritation to the eyes, skin, and respiratory system. In the backyard, pool and garden shed.
Using the exposure assumptions described in this unit for short-term exposures, short-term aggregate risk was estimated for combined oral and inhalation exposure in adults applying naphthalene acetate products with a paint-airless sprayer. Ingestion: After ingestion naphthalene causes abdominal cramps with nausea, vomiting and diarrhoea. Chronic (long-term) exposure of workers and rodents to naphthalene has been reported to cause cataracts and damage to the retina. Canadians' exposure to naphthalene is attributed predominantly to indoor air, because indoor air levels generally exceed ambient air levels, and because of the greater time spent indoors. Documentation for these values is available in the Air Toxics Hot Spots Program Guidance Manual for the Preparation of Health Risk Assessments 2015. Inhalation of naphthalene may cause skin and eye irritation; gastrointestinal symptoms, such as nausea, vomiting, abdominal cramps, and diarrhea Naphthalene is absorbed following oral, dermal, and inhalation exposure and its association with hemolytic anemia is well described in most textbooks. It rarely occurs in suicidal attempts in adults and in accidental ingestion by children. The inhalation unit risk for inhalation exposure to 1,4-DCB established by OEHHA is 1.110 2 (mg m 3) 1, which is similar to that of naphthalene by a factor of three . 5.2 and 5.3). 2001; Long et al. Use of
Industrial naphthalene-fume poisoning, chiefly with skin manifestations (Touraine and Menetrel 1934, Fanburg 1940) and especially naphthalene cataract (Bouchard and Charrin 1886, Michail and Vancea 1927) have also been often reported and investigated. Acute (short- term) exposure of humans to naphthalene by inhalation, ingestion, and dermal contact is associated with hemolytic anemia, damage to the liver, and neurological damage. But it has rarely Case Report. Human exposure to naphthalene is primarily through inhalation, although it can be ingested and absorbed through the skin. The male rat was the most sensitive sex and species tested by NTP (1992; 2000) in the inhalation carcinogenesis studies of naphthalene. Naphthalene consists of two benzene rings that are fused together; the resulting molecule is still aromatic, and undergoes the reactions that are typical of benzene Naphthalene may also damage the liver, kidneys and the eyes. Acute exposure of humans to naphthalene by inhalation, ingestion, and dermal contact is associated with haemolytic anaemia, liver damage, neurological damage in infants, and death. Physical Properties Physical description A white crystalline volatile solid with A white crystalline volatile solid with A white crystalline volatile solid with Boiling point 424F Molecular weight 128.2 Freezing point/melting point 176F Vapor pressure 0.08 mmHg Flash point 174F Vapor density 4.42 Specific gravity 1.15 Ionization potential 8.12 eV 6 more rows Noun: 1. naphthalene poisoning - toxic condition resulting from inhaling or ingesting naphthalene Serious poisoning in animals is reported to cause tremors and hepatic necrosis. Though it is freely available around this country, poisoning has never been reported in the literature. Naphthalene causes lung toxicity in mice, but not rats, following either intraperitoneal injection or inhalation exposure. DO NOT use it to treat or manage an actual poison exposure. Cataracts have also been reported in workers acutely exposed to naphthalene by Sources and route of human exposure Naphthalene toxicity may occur by all routes of exposure, whether by inhalation of vapours, ingestion and by dermal or ocular contact [1-3]. Naphthalene is a primary irritant upon direct skin contact and may be acutely irritating to the eyes. Ingestional naphthalene mothball poisoning leading to prolonged haemolysis and methaemoglobinaemia can present with diagnostic and therapeutic challenges. 2-methoxy-5-nitroanaline inhalation cancer removed. Preventing Exposure to Chemicals in Mothballs Adults, children, and pets can be exposed to naphthalene in mothballs by: Breathing in vapors (inhalation) Swallowing (ingestion) Touching (skin or dermal contact) You are most likely to be exposed to naphthalene by inhaling the vapors. ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Naphthalene. Toxicity from naphthalene and paradichlorobenzene is most dangerous with ingestion, but documentation shows that inhalation of vapors and dermal exposure can cause serious effects and irritation to dogs as well. The US EPA has classified naphthalene as a Group C, possible human carcinogen. choking from inhalation of vomit after inhalant use; or; Perhaps the most significant toxic effect of chronic exposure to inhalants is widespread and long-lasting damage to the brain and other parts of the nervous system. The most likely source of exposure to significant amounts of naphthalene is occupational inhalation of the vapour, since its principal use is in industry [1]. Ingestion or inhalation can cause headaches, nausea, vomiting, dizziness, depression, and stomach pain.
The presence of respiratory tract tumors in animals following naphthalene exposure by inhalation is sufficient to demonstrate carcinogenicity in these model systems, but the quantification of human cancer risk at low exposure levels based on these studies is a point of considerable debate. Clinically, patients present with acute onset of dark brown urine, watery diarrhea, and non-bloody bilious vomiting 48-96 hours after exposure. f High exposure to Naphthalene can cause headache, fatigue, confusion, tremor, nausea and vomiting. Acute (short-term) exposure of humans to naphthalene by inhalation, ingestion, and skin contact has been associated with hemolytic anemia, liver damage, and neurological damage. The results of this study indicate that the LC 50 for naphthalene vapour in Wistar albino rats is greater than 77.7 ppm, (0.4 mg/L) naphthalene.
Synonym (s): naphthalin, tar camphor. What are the causes of naphthalene balls? Introduction Naphthalene is commonly found in moth repellent products such as mothballs in developing countries. In mice, the injury is dose-dependent and Clara cell-specific. Naphthalene, NTP TR 410 Nonneoplastic lesions attributed to naphthalene exposure were observed in the nose and lungs of mice of both sexes. Ammonia Go to Step 7. Naphthalene poisoning occurs primarily as a result of accidental mothball ingestion, causing symptoms such as nausea, vomiting, hematuria and severe respiratory, neurologic and hepatic effects. This article is for information only. f Inhaling Naphthalene can irritate the nose and throat. f High exposure to Naphthalene can cause headache, fatigue, confusion, tremor, nausea and vomiting. f Exposure to Naphthalene may cause a skin allergy. fNaphthalene may damage the liver and kidneys. fRepeated high exposure may cause anemia (low blood count). fNaphthalene is a COMBUSTIBLE SOLID. It may also be repeated exposure can cause clouding of the eye lens (cataract), which may damage vision. Sensitive individuals can Chronic inhalation exposure resulted in increased incidences of nonneoplastic and neoplastic lesions in the nose of rats (Abdo et al. 410. Naphthalene (mothball) is a commonly used deodorizer in the Indian subcontinent, including Sri Lanka. If remediation is not complete, then go to Step 4.B. Methods: This review is an update for the clinicians to understand the pharmacology, clinical features, laboratory evaluation, and treatment for naphthalene toxicity. Acute (short- term) exposure of humans to naphthalene by inhalation, ingestion, and dermal contact is associated with hemolytic anemia, damage to the liver, and neurological damage. DO NOT use it to treat or manage an actual poison exposure. Exposure to naphthalene can cause haemolytic anaemia, which doesn't prevent it being an ingredient in lavatory-bowl deodorant blocks. lene.
Naphthalene is a white solid substance with a strong smell. As little as one mothball can result in toxicity in children. Motor Oil. Naphthalene exposure can occur if you breathe air that contains naphthalene, if you drink liquids containing naphthalene, or if products containing naphthalene are touched or accidentally eaten. This can cause organ damage.
An oil refinery or petroleum refinery is an industrial process plant where petroleum (crude oil) is transformed and refined into useful products such as gasoline (petrol), diesel fuel, asphalt base, fuel oils, heating oil, kerosene, liquefied petroleum gas and petroleum naphtha. Damage from inhalation of the fumes can be severe and occa-sionally fatal. 3.3. A 19-year-old woman ingested 12 mothballs, and presented two days later with haemolysis and methaemoglobinaemia. The metabolite of naphthalene (usually -naphthol) is the main cause of poisoning. 92-3141. This article is for information only. This article is for information only. DO NOT use it to treat or manage an actual poison exposure. Aims: To estimate exposures to benzene and naphthalene among military personnel working with jet fuel (JP-8) and to determine whether naphthalene might serve as a surrogate for JP-8 in studies of health effects. If swallowed, naphthalene can damage red blood cells, causing kidney damage and many other problems. Extended exposure to mothballs can also cause liver and kidney damage. The skin is the largest organ of your body and a common exposure site for liquid and airborne chemicals. As little as 250500 mg may produce hemolysis in a patient with G6PD deficiency.
through the skin is another route of entry. Naphthalene Methemoglobinemia Hemolytic anemia Metabolic acidosis Seizures 1. Finally, NA inhalation induces acute cytotoxicity Introduction Naphthalene is commonly found in moth repellent products such as mothballs in developing countries. Poisoning from naphthalene destroys or changes red blood cells so they cannot carry oxygen. Cataracts have also been reported in workers acutely exposed to naphthalene by inhalation and ingestion. External gaseous exchange then takes place, using the principle of diffusion: Naphthalene is a white solid substance with a strong smell. Hazards of Crude Oil Components All of these components are inhalation hazards Some also pose a dermal exposure hazard Exposures may result in either acute or chronic effects Remember the Routes of Entry Inhalation Absorption Ingestion Injection. Naphthalene poisoning is a rare form of toxicity that may occur after ingestion, inhalation, or dermal exposure to naphthalene-containing compounds such as mothballs. Exposure to naphthalene can cause more serious effects, including hemolytic anemia. Systemic poisoning is the result of inhalation of fumes from molten sub-stances containing chlorinated naph-thalenes rather than from contact with cold solids. landuse scenario: body surface area, ingestion rates, body weight and soil adherence factors. The substance with the formula C 20 H 12 is one of the benzopyrenes, formed by a benzene ring This can cause organ damage. Sources and route of human exposure Naphthalene toxicity may occur by all routes of exposure, whether by inhalation of vapours, ingestion and by dermal or ocular contact [1-3]. Human. Inhalation. Nearly all materials that are airborne can be inhaled. Human exposure to naphthalene (NA), an acute lung toxicant and possible human carcinogen, is primarily through inhalation. [citation needed] Naphthalene was introduced in 1841 by Rossbach as an antiseptic to counteract typhoid fever. Although naphthalene keeps invaders at bay, it does not affect the termites.Naphthalene not only keeps ants and ACUTE TOXICITY DATA: Naphthalene, NTP TR 410 Nonneoplastic lesions attributed to naphthalene exposure were observed in the nose and lungs of mice of both sexes. Although it is one of the most widely used pesticides, prolonged exposure to this substance should be avoided, as its inhalation, ingestion or contact can cause severe damage that must be treated immediately by a specialist.
This is considered the worst case scenario for the aggregate risk assessment. Those with glucose-6-phosphate dehydrogenase (G6PD) deficiency are especially susceptible. Naphthalene Toluene. An MRL of 0.0007 ppm (3x10-3 mg/m3) for chronic inhalation exposure to naphthalene is based on a Accidental or intentional poisoning by naphthalene has been reported by swallowing, skin contact, and inhalation. Patient history is vital during workup, while detection of methemoglobinemia and cyanosis requires prompt therapy consisting of methylene blue and exchange transfusion. Naphthalene The poison repels their major enemy, ants, as well as microscopic worms, bacteria and fungus in the soil. NTP: Toxicology and carcinogenesis studies of naphthalene in B6C3F1 mice (inhalation studies). Additional groups naphthalene exposure. This can cause organ damage. Poisoning from naphthalene destroys or changes red blood cells so they cannot carry oxygen. This is based on the inadequate data of carcinogenicity in humans exposed to naphthalene via the oral and inhalation routes, and the limited evidence of carcinogenicity in animals via the inhalation route. Absorption. Ingestion, either accidental or by deliberate self-harm, can occur due to its abundance as well as its candy-resembling appearance. Be aware that you can also breathe in naphthalene vapours from clothes that have been stored in moth balls. Effects of Exposure Symptoms : Excessive inhalation vapors cause rapid breathing, excitability, staggering ,headache, fatigue, nausea and vomiting, dizziness, In 1989 there were 2,300 reported ingestion of naphthalene ball by children under the age of 6 in United States alone . Naphthalene: 3D: Download 3D: Naphthalene is a white crystalline solid, derived from coal tar, with a characteristic odor of mothballs which is not a coincidence, since naphthalene is frequently used in mothballs. Incidence and Severity of Nonneoplastic Lesions in the Noses of Rats in a See annual publication for most recent information. Breathing the fumes from mothballs may cause headaches and dizziness and may irritate the skin, eyes, and throat. Majority of the cases have been reported in young children with accidental exposure to naphthalene balls . This can cause organ damage. inhalation exposure to naphthalene. The amount necessary to produce lethargy or seizures is not known but may be as little as 12 g. Several infants developed serious poisoning from clothes and bedding that had been stored in naphthalene mothballs. Based on these air monitoring data, the level of naphthalene detected (0.0002 ppm) was below its odor threshold. Since that time new data have become available, which have been incorporated in this Monograph, and taken into consideration in the present evaluation. NA inhalation exposure induces the expression of several genes or pathways related to lung tumor development, but with minor differences between males and females.
The pesticides in mothballs are chemicals known as naphthalene and p-dichlorobenzene. from mothballs). A reference concentration (RfC) for inhalation exposure to naphthalene has not been derived (U.S. EPA, 1991, 1992). from incomplete combustion) and/or indoor air (i.e. She was treated with red blood cell transfusions, intravenous methylene To address this concern, mice were exposed to naphthalene by inhalation (1.515 ppm; 24 h), thereby bypassing first-pass hepatic involvement. Inhalation of naphthalene may cause skin and eye irritation; gastrointestinal symptoms, such as nausea, vomiting, abdominal cramps, and diarrhea; neurologic symptoms, such as confusion, excitement, and convulsions; renal problems, such as acute renal shutdown; and hematologic features, such as icterus and severe anemia. Naphthalene poisoning is a rare form of toxicity that may occur after ingestion, inhalation, or dermal Introduction. The LD 50 is 1.8 g/kg in adult rats. The US National Toxicology Program (NTP) held an experiment where male and female rats and mice were exposed to naphthalene vapors on weekdays for two years. CAREX defines exposure to naphthalene as inhalation exposure at work at levels exceeding those encountered in non-occupational settings, such as exposure due to inhaling urban air (i.e. Naphthalene is a white solid substance with a strong smell. naphthalene by inhalation at concentrations of 0, 10, 30, or 60 ppm for 6 hours plus T. 90 (12 minutes) per day, 5 days per week for 105 weeks. Exposure to the hydrocarbons in motor oil can cause cancer. guidance. Though it is freely available around this country, poisoning has never been reported in the literature. Acute hemolysis may occur, especially in patients with G6PD deficiency. Occupational exposure as a painter was considered by previous Working Groups in 1988 and 2007 (IARC, 1989, 2010a). Acute exposure of humans to naphthalene by inhalation, ingestion, and dermal contact is associated with haemolytic anaemia, liver damage, neurological damage in infants, and death. Naphthalene. DO NOT use it to treat or manage an actual poison exposure. Petrochemicals feedstock like ethylene and propylene can also be produced directly by cracking crude oil DO NOT use it to treat or manage an actual poison exposure. Naphthalene poisoning is an uncommon poisoning due to its pungent smell, taste, insolubility in water, and poor absorption from the gut. Vital sign abnormalities include fever, tachycardia, Naphthalene oral cancer added. A 33-year-old Sri Lankan woman